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ALLAN LAB

We are a research group at De Montfort University that focusses on microbiological research. Our interests are bacterial biofilms, host-pathogen interactions, mechanistic studies, and the development and testing of treatments.

Latest News

Lab Members

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PhD Student

Jasira Patel

Jasira's research focusses on understanding the interplay between harmless commensal bacteria and the respiratory pathogen Haemophilus influenzae, determining whether the commensals can be used as future therapeutics for infection.

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PhD Student

Divine Derefaka

Divine's research focusses on the development of a humane respiratory mucosal model that replaces the use of animal models and animal-based products to investigate the role of Streptococcus pneumoniae biofilms in respiratory infections.

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PhD Student

Harini Satkunarasa

Harini's research focusses on the development of a lab-based laundering model for the investigation of biofilm formation, antimicrobial/disinfectant resistance, and biofilm-removal interventions.

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MRes Student

Lord Cudjoe

Lord's research focusses on the development and evaluation of novel phytochemicals as nebulisable treatments for respiratory tract biofilm infections.

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PhD Student

Katie Hussain

Katie's research focusses on investigating the role of biofilms within industrial healthcare, pharmaceutical and hospitality laundries. She explores their impact on infection control, antibiotic resistance, wastewater and the environment.

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MRes Student

Muhammad Atif

Muhammad's research focusses on understanding the interactions taking place within interkingdom biofilms, determining how bacteria and fungi contribute towards respiratory infection.

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Recent & Key Publications

Multi-excitation Raman spectroscopy for label-free, strain-level characterisation of bacterial pathogens in artificial sputum media (2022).

Lister AP, Highmore CJ, Hanrahan N, Read J, Munro APS, Tan S, Allan RN, Faust SN, Webb JS, Mahajan S.

Analytical Chemistry.

PMID: 34978813

DOI: 10.1021/acs.analchem.1c02501

[Article Link]

An integrated model system to gain mechanistic insights into biofilm-associated antimicrobial resistance in Pseudomonas aeruginosa MPAO1 (2020).

Allan RN*, Varadarajan AR*, Valentin JDP*, Castaneda Ocampo OE, Somerville V, Pietsch F, Buhmann MT, West J, Skipp PJ, van der Mei HC, Ren Q, Schreiber F, Webb JS, Aherns CH.

npj Biofilms and Microbiomes.

PMID: 33127897

DOI: 10.1038/s41522-020-00154-8

[Article Link] *Equal contribution

Targeting Biofilms: Current and Prospective Therapeutics (2017).

Allan RN*, Koo H, Howlin RP, Stoodley P & Hall-Stoodley L.

Nature Reviews Microbiology.

PMID: 28944770

DOI: 10.1038/nrmicro.2017.99

[Article Link]

Pronounced metabolic changes in adaptation to biofilm growth by Streptococcus pneumoniae (2014).

Allan RN, Skipp P, Jefferies J, Clarke SC, Faust SN, Hall-Stoodley L & Webb J.

PLoS One.

PMID: 25188255

DOI: 10.1371/journal.pone.0107015

[Article Link]

Photos

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Opportunities

The Allan lab is happy to consider all enquiries about available positions.

 

Details on opportunities can be found through the following link:

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@allan-lab.bsky.social

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@rayallan1980

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